It is felt that some strains of Borellia give off neurotoxins and that there may be more than one type of neurotoxin given off. This may account for why some people are sicker than others and why, perhaps, some with Lyme disease do not respond much to antiobiotics. What happens with neurotoxins, such as with Ciguetera poisoning, is that the poisons keep recirculating through your body due to what is called enterohepatic circulation where your body is not fully able to excrete these neurotoxins. It has been suggested by a Dr. Richie Shoemaker that those with Lyme disease and other illnesses where neurotoxins are implicated should take Questran (the name brand of cholestyramine) which is a cholesterol lowering drug. The theory behind this is that the strong positive charge of the cholestyramine will bind to the negative charge of the neurotoxin (or cholesterol as this is what the medication is commonly used for) and thus promote their excretion by preventing the enterohepatic circulation.
Having read much on this, I contacted my LLMD (Lyme Literate Doctor) and asked if I could try some Questran. He said he would gladly fill a script, however, he tried it with 100 of his patients and not one of them received any benefit from it, only adverse things such as bloating and constipation as it is very fatty. I also spoke with some other Lyme sufferers who said they too did not receive any benefit. As well, it can be a real pain to take as it can also interfere with antibiotics and supplements and so needs to be taken with food a few hours apart from anything else. Therefore, although Dr. Shoemaker is promoting this as a possible cure-all for the symptoms of Lyme, I am skeptical.
One idea that is far less risky is to try using Oat Bran (this will not work with regular oats) as it contains the polysaccharide Betaglucan – a soluble part of dietary fiber – that interrupts the enterohepatic circulation, absorbing bile acid and carrying it safely out of the body – neurotoxins included. Those with Lyme and other illnesses often avoid eating anything with gluten (a good idea as celiac tests are often only about 50-60% reliable), as do those with Celiac disease, so the problem with oats or oat bran is that they are often contaminated with wheat because oats are typically grown on land used to grow wheat as well, and/or packaged in facilities that package wheat products. BUT, I did find a company in Canada called Only Oats that guarantees their oats to be gluten-free from rigid testing and they do not grow the oats on fields used for wheat as well, and products are packaged in a wheat-free facility. The best part, they sell oat bran! Now, the shipping to the US can be pricey – looks to be a flat $20. I ordered their 5 lb 8 oz. bag of gluten-free oat bran and will give it a try. Try to take the oat bran apart from your medications or supplements as, if it works, it may bind to and help excrete the antibiotics or whatever else you are are taking besides, hopefully, the neurotoxins. Lastly, I had a doctor once tell me that he had patients take oat bran to help with removing mercury from their body when they had mercury poisoning, so maybe there is something to this!
Only Oats is the place to buy the gluten-free oat bran.