Lyme Disease Symptoms

So this part can be really tricky, as symptoms for Lyme are vast and vary from person to person, which is why Lyme disease is often misdiagnosed as something else. The symptoms for Lyme can range from slight fatigue, to joint pain, to depression, seizures, and even cardiac failure. The following is a superb comprehensive list of Lyme disease symptoms from The Canadian Lyme Disease Foundation:

Lyme Disease (commonly misspelled as Lime or Lymes ) symptoms may show up fast, with a bang, or very slowly and innocuously. There may be initial flu-like symptoms with fever, headache, nausea, jaw pain, light sensitivity, red eyes, muscle ache and stiff neck. Many write this off as a flu and because the nymph stage of the tick is so tiny many do not recall a tick bite.

Lyme Disease, SYMPTOMS & CHARACTERISTICS, a compilation of peer-reviewed literature reports

The classic rash may only occur or have been seen in as few as 30% of cases (many rashes in body hair and indiscreet areas go undetected). Treatment in this early stage is critical. The Lyme Rash

If left untreated or treated insufficiently symptoms may creep into ones life over weeks, months or even years. They wax and wane and may even go into remission only to come out at a later date…even years later.

With symptoms present, a negative lab result means very little as they are very unreliable. Read here. The diagnosis, with today’s limitations in the lab, must be clinical.

Many Lyme patients were firstly diagnosed with other illnesses such as Juvenile Arthritis, Rheumatoid Arthritis, Reactive Arthritis, Infectious Arthritis, Osteoarthritis, Fibromyalgia, Raynaud’s Syndrome, Chronic Fatigue Syndrome, Interstitial Cystis, Gastroesophageal Reflux Disease, Fifth Disease, Multiple Sclerosis, scleroderma, lupus, early ALS, early Alzheimers Disease, crohn’s disease, ménières syndrome, reynaud’s syndrome, sjogren’s syndrome, irritable bowel syndrome, colitis, prostatitis, psychiatric disorders (bipolar, depression, etc.), encephalitis, sleep disorders, thyroid disease and various other illnesses.

If you have received one of these diagnoses please scroll down and see if you recognize a broader range of symptoms.

If you are a doctor please re-examine these diagnoses, incorporating Lyme in the differential diagnoses.

The one common thread with Lyme Disease is the number of systems affected (brain, central nervous system, autonomic nervous system, cardiovascular, digestive, respiratory, musco-skeletal, etc.) and sometimes the hourly/daily/weekly/monthly changing of symptoms.

No one will have all symptoms but if many are present serious consideration must be given by any physician to Lyme as the possible culprit. Lyme is endemic in Canada period. The infection rate with Lyme in the tick population is exploding in North America and as the earth’s temperature warms this trend is expected to continue.

Symptoms may come and go in varying degrees with fluctuation from one symptom to another. There may be a period of what feels like remission only to be followed by another onset of symptoms.

PRINT AND CIRCLE ALL YES ANSWERS ( 20 yes represents a serious potential and Lyme should be included in diagnostic workup )

Symptoms of Lyme Disease

The Tick Bite (fewer than 50% recall a tick bite or get/see the rash)
Rash at site of bite
Rashes on other parts of your body
Rash basically circular, oval and spreading out (more generalized)
Raised rash, disappearing and recurring

Head, Face, Neck

Unexplained hair loss
Headache, mild or severe, Seizures
Pressure in head, white matter lesions in brain (MRI)
Twitching of facial or other muscles
Facial paralysis (Bell’s Palsy, Horner’s syndrome)
Tingling of nose, (tip of) tongue, cheek or facial flushing
Stiff or painful neck
Jaw pain or stiffness
Dental problems (unexplained)
Sore throat, clearing throat a lot, phlegm ( flem ), hoarseness, runny nose


Double or blurry vision
Increased floating spots
Pain in eyes, or swelling around eyes
Oversensitivity to light
Flashing lights/Peripheral waves/phantom images in corner of eyes


Decreased hearing in one or both ears, plugged ears
Buzzing in ears
Pain in ears, oversensitivity to sounds
Ringing in one or both ears

Digestive and Excretory Systems

Irritable bladder (trouble starting, stopping) or Interstitial cystitis
Upset stomach (nausea or pain) or GERD (gastroesophageal reflux disease)

Musculoskeletal System

Bone pain, joint pain or swelling, carpal tunnel syndrome
Stiffness of joints, back, neck, tennis elbow
Muscle pain or cramps, (Fibromyalgia)

Respiratory and Circulatory Systems

Shortness of breath, can’t get full/satisfying breath, cough
Chest pain or rib soreness
Night sweats or unexplained chills
Heart palpitations or extra beats
Endocarditis, Heart blockage

Neurologic System

Tremors or unexplained shaking
Burning or stabbing sensations in the body
Fatigue, Chronic Fatigue Syndrome, Weakness, peripheral neuropathy or partial paralysis
Pressure in the head
Numbness in body, tingling, pinpricks
Poor balance, dizziness, difficulty walking
Increased motion sickness
Lightheadedness, wooziness

Psychological well-being

Mood swings, irritability, bi-polar disorder
Unusual depression
Disorientation (getting or feeling lost)
Feeling as if you are losing your mind
Over-emotional reactions, crying easily
Too much sleep, or insomnia
Difficulty falling or staying asleep
Narcolepsy, sleep apnea
Panic attacks, anxiety

Mental Capability

Memory loss (short or long term)
Confusion, difficulty in thinking
Difficulty with concentration or reading
Going to the wrong place
Speech difficulty (slurred or slow)
Stammering speech
Forgetting how to perform simple tasks

Reproduction and Sexuality

Loss of sex drive
Sexual dysfunction
Unexplained menstral pain, irregularity
Unexplained breast pain, discharge
Testicular or pelvic pain

General Well-being

Phantom smells
Unexplained weight gain, loss
Extreme fatigue
Swollen glands/lymph nodes
Unexplained fevers (high or low grade)
Continual infections (sinus, kidney, eye, etc.)
Symptoms seem to change, come and go
Pain migrates (moves) to different body parts
Early on, experienced a “flu-like” illness, after which you have not since felt well.
Low body temperature

Allergies/Chemical sensitivities

Increased effect from alcohol and possible worse hangover



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  3. claire bishop
    April 15, 2011 at 9:14 am

    My name is Claire Bishop and I’m volunteering for the Ridgefield Lyme disease Task Force. My aim is to get the word out about the forthcoming May Health fair to fellow Lyme sufferers.
    Please feel free to contact me at

    Free Lyme Disease Patient Seminar and Health Fair
    Tuesday Evening May 3 at West Conn Westside Student Center – 6 to 9 pm

    The Impact of Lyme Disease: Body and Mind

    April 5, 2011-Patients seeking support in their recovery from Lyme and other tickborne diseases will want to attend thefree seminar and health fair event The Impact of Lyme Disease: Body and Mind scheduled for Tuesday evening May 3 at Western Connecticut State University Westside
    Student Center, 6 – 9 pm. Speakers include Dr. Robert Bransfield, president of the International Lyme and Associated Diseases Society (ILADS), Pat Smith, president of the Lyme Disease Association (LDA) and Denise Lang- Grant, LPC, author of the bestselling book “Coping with Lyme Disease: A Practical Guide to Dealing with Diagnosis and Treatment.” The health fair, which opens an hour prior to the seminar, features practitioners, products and services specifically related to tickborne diseases. Health fair doors open at 6 pm with speakers starting at 7. For additional information contact Karen Gaudian at The event is sponsored by the Ridgefield Lyme Disease Task Force in recognition of Lyme Awareness Month.

    The West Conn Westside Student Center is located at 43 Lake Avenue Extension,
    Danbury, CT 06810. Driving directions to the Westside location and a map are available at:

    May is Lyme Awareness Month.

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  4. David
    September 5, 2011 at 12:13 pm

    I have just been diagnosed, after a year of inflammed knee symptoms. Left knee was inflamed in Maine and the Sports Doc, tested my blood and test was positive. Prescribed Doxycycline one kne was affected, now both, and I’m getting various slight flu like sysmtoms. Is this normal? what else should I consider?

    • Danielle
      September 5, 2011 at 8:11 pm

      Hi, David. Sorry to hear but glad you were tested finally. Well, the symptoms are normal for Lyme disease, and symptoms can migrate. If you are still on the Doxy, you could be having what is called a herxheimer reaction – a worsening of symptoms due to killing of the bad guys. If I were you, I would try and get myself to a Lyme literate doctor as soon as possible as you really want to treat Lyme disease aggressively. If you go to my post here, you will find a few places that will help you locate LLMDs that are close to you for free

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  5. Cathy
    December 6, 2011 at 9:36 am

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    • Danielle
      December 7, 2011 at 1:00 pm

      Gosh, Cathy, I am so very sorry to hear of your sister’s story and what has transpired. You are very brave and thank you for sharing with others on here. Wishing you and your sister a positive outcome if you are somehow able to get her proper treatment.

      • August 1, 2014 at 11:20 am

        First, you need to identify the tick. If it prevos to be a deer tick (aka: black-legged tick) officially refered to as Ixodes scapularis’, you can proceed with pursuing testing for Lyme, though any imbedded tick of this type found on you in an area where Lyme is a problem, should be considered a high-risk bite that most likely needs immediate antibiotic therapy (Don’t Wait for the test results, Olga! See your doc NOW!)As far as getting that Tick tested, either look up or call your local county’s Dept. of Health Human Services. Also, a call to the nearest University’s Co-op Extension Service is often fruitfull.There is usually atleast One lab in each state in the Northeast U.S. that will test the tick [for the presence of the Borrelia Burgdorferi bacteria] but they usually charge somewhere around $45 to $75/ tick often only accept the ticks via express shipment at the beginning of the week. You can usually order up a kit in advance to ship the sick tick to em.Don’t expect the results right away it takes a few days to over a week. That’s it!

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  6. Trisha
    June 27, 2012 at 12:57 pm

    Hi. I have been reading on your site. Lyme disease cannot be cured? I got bit by a tick about 5 weeks ago. I had many blood test done. The tick panel came back all negative. I have read it is not very accurate. I have also seen people talk about Igenex Labs in Cali. How does a person get that started and what test do you ask for. There are so many listed on the site. They are doing MRI test on me. Could my child get it from me from breast feeding.

    • Christina Dolly
      June 6, 2014 at 11:55 pm

      Symptoms..You will know quick flu like symptoms happened very quick with me. I felt like I had a sore throat 24/7 but the ring like a ring worm with dots around it and a fleshy color inside with a dot is a dead give away. Your eyes will look blood shot 24/7. Your arms will get sore. Your neck unbearably stiff throbbing feeling. Start your treatment if you have the ring. I do Cowden’s program by NutraMedix. I don’t put drugs in my body. it is 100% herbal. I will give you the number 561-745-2917 I say alot of prayers and do alot of crying for mercy. You be blessed. I pray you are not sick. I wouldn’t breast feed. I would be to scared. I have no enemies but I wouldn’t wish this on them if I did. Lambs have epidemic lymes disease. They are dying. Quail eat the ticks so do pheasant..I have heard in the first 30 days with drugs you can be cured. You know what.. that is what man says. God can heal anyone anytime on His time. That is what I am shooting for..God bless you

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    • Christina Dolly
      June 7, 2014 at 12:03 am

      Also if just band 41 was positive get treated you have the tail-end of lymes disease and if not treated you will get WORSE and if you already have the symptoms don’t wait..head-ache…tired..hard to breath..flu…strange cough…sore throat…sore…popping feeling in your whole body…like something is crawling up your head..down your skin…red eyes…hard to walk..use your arms…dizzy…throw up in the night…fever…chillls…cold sweats…stomach stays swollen…skin looks weird…hair changes texture….bottom of your feet burns…1 knee at a time hurts…neck hurts so bad you think it is not yours… that there are metal rods up both sides pushed into your brain..don’t take any chances…I don’t want any of this and more so much more for you or anybody…God bless you…Be scared..take action

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  7. JasonMChicago
    June 29, 2012 at 7:18 pm


    In case you’d like another opinion… if it was me, I would NOT wait for a lab test. Yes, I would go ahead and get Igenex ordered but why wait? Lyme is a bacteria and bacteria multiple very quickly. The longer you wait the more there are to kill off. I would start doing things to build the immune system and detox the die-off of Lyme. What would I do? I would get High dose Vitamin C IV weekly (50 gram+ finding a doctor to do this is a pain but WAY WORTH IT), I would take high doses of good quality probiotics daily, I would take Cat’s Claw or Samento daily, take other mico-bacterials (I would pick from Buhner’s book), alkalize my body, etc. There are LOTS of things to do… but I would jump on it right now (if it was me)!!! None of these things would hurt me and can only help. Just info on “what I would do.”


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  8. Trisha
    July 5, 2012 at 11:23 pm

    Jason thank you for all the information. Have you had Lyme disease? I am wanting to know how other people felt before they knew they had it. Thanks for all the herbal information also. How does a person get the lab test going and what test do you order. There are so many. It looks like you buy one then have a lab send it. ?? Has anyone been through all this so they can help me.

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      August 3, 2014 at 2:14 am

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  9. JasonMChicago
    July 6, 2012 at 11:10 am

    Hi there… yes I have Lyme disease. I probably had it for a decade or MORE before I got diagnosed. When I got diagnosed, I was literally dying. Here are the symptoms I had before getting diagnosed.

    -Digestive issues (gas, bloating, “lactose intolerance” all kinds of stuff)
    -Emotional ups and downs
    -Muscle pain/tightness
    -Severe Neck pain
    -Facial pain
    -Anxiety (this came at the VERY end, I had severe anxiety)
    -TMJ (involuntary movement of my jaw)
    -Sleep problems (for years it was always tired but then it turned into can’t sleep)
    -Joint Pain (this came at the very end)
    -Shooting pains in legs (like electricity or something)
    -Sensitivity to light/sound (this was for a little while)

    There is not a lot of info on Lyme but when I kept googling I thought I had “fibromyalgia” which is a nonsense diagnosis… but I didn’t know that at the time. I finally went to a fibro-specialist who happened (thank God) run a Lyme test. Boom! It came back “slightly positive.” I quickly knew it was Lyme. I just knew in my gut that something MAJOR was wrong. I took antibiotics and it didn’t work. I then did a HUGE MAJOR effort to get well. I’m doing really well. I don’t put a percentage on things or timeframe because I’ve learned that doesn’t help. I actually have to go to my vitamin C IV right now so can’t write more but my suggestion is PLEASE do not wait for a positive test. It really has little meaning. It is the symptoms that matter. Google around and see what others say. If you have the symptoms then start some kind of program. I did a standard Western Blot but if I needed confirmation I would only trust IGENEX (they are the best but still only 70% accurate). Again, I personally didn’t need a through test, I just knew when the doctor said you have a “Lyme infection” it was it. One thing you’ll learn on your journey is to trust your gut.

    Taking probiotics on an empty stomach is a great thing to do daily to help build good bacteria.

    • Christina Dolly
      June 6, 2014 at 11:28 pm

      My story is long but my lymes disease longer…The Dr. said it was a spider bite 1 year 5 months ago..He was wrong…The Dr. report said I never saw him..Another Dr. same office said I am not sick… I believe I have lymes disease..You are so right listen to your heart and body…The one that is failing you and you are told you are not sick…I had a blood test done and band 41 was reactive…for one year I was sick witht the flu. I promised myself this year I would not be sick. Something I have no control over yet but I am not throwing in the towel yet. I kept my body as God’s Temple even being as old as dirt. I am not going to let some foolish Dr.’s bury me yet because of their own stupity. I am doing Cowden’s treatment by NutraMedix month 3 now. I am to feel worse before better. I can’t judge worse so I don’t know better as of yet. The whole time I had different days with different happenings but the last two days have been all the symptoms like a rolle polle all at once. It has been really hard. I do not take drugs or pain killers so the pain has topped 200 out of ten. When I can’t take it anymore I really cry for Mercy and beg God to take it and heal not only me but anyone that calls on His Name for HEALING. I have been through alot of things in my life but this is the hardest. I was healthy..built…lifted weights…worked out about 3 hours a day or night so this is awe and shock for me. I believe being in shape might be saving me somewhere along the line with this plus I have the FAITH of the mustard seed…I know God is going to heal me…And you.. God bless all of you…I want healing for us all…

      • Lymee1
        February 18, 2015 at 1:10 am

        You seem to have researched the disease quite extensively. I want to point out that it’s called “Lyme disease” there’s no “s” on the end

    • August 2, 2014 at 10:47 pm

      Hey guys,. . There is a movie I caught on tesevilion (station SBS in Australia) a number of times when I was younger, and I always seemed to catch the same scene. I was wondering if anyone knew what the movie was it’s kinda bugging me.. . You’ll laugh when you find out what the scene I remember involved; it sounds so dodgy! Hehe. My memory isn’t the greatest, and I may be putting down things that weren’t there, but anyway, I’ll give it a go. . . The film was a comedy, I think, and was either Italian or Spanish. Anyway, the part I remember is that there were two couples in an apartment somewhere. One of the couples is quite liberated, and the other is more uptight, but they have come to the apartment in order for the uptight couple to have sex with the liberated couple. As some kind of introduction, the two guys go into one room and the two girls go into another. There is some joke about how they’re meant to be having foreplay with each other (the two men together and the two women), but the women do and lie about it, while the men don’t, but pretend they do (I remember a scene filmed to look initially like the men are blowing each other, but really they are lighting cigarettes). Then they are all planning to get together when the liberated guy looks out the window and sees some kids stealing his motorbike.. . He runs off to get it back and it has been dumped in a river. Meanwhile the uptight guy has sex with the two women and when the second guy gets back he’s really disappointed that they didn’t wait for him. But then they all hook up, the four of them. And I think what happens is that when retrieving his bike from the river, the guy picked up some skin irritation and passed it on to the others.. . Hope someone can help, it’s been bugging me what this movie is called! Hope the description helps as I say, my memory is pretty hazy!.

    • August 3, 2014 at 10:29 am

      fish on! thats great news brother, glad to hear it. Im fnieelg some improvement myself. Seven months on antibiotics. Diagnosed in 08 . I have late stage lyme and babesia.

  10. zoomie z
    September 4, 2012 at 8:12 pm

    and yes this would sum up the long list of my symptoms. always good to check with list when i feel i am going insane or hypochondriac!

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    • Christina Dolly
      June 6, 2014 at 11:34 pm

      Any help with this disease would be appreciated. I am doing the NutraMedix support program Cowden’s month 3 program but what else can I do. I want to beat this. I want my body back…My body in Christ…I feel like I have no control…God bless you all

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    • August 2, 2014 at 1:44 am

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      I’m about halfway throguh getting your meds into the PatientsLikeMe tracker. I’m actually making a slideshow for it, then I’m going to do a voiceover on the slides. Right now I just have the screencaps. I also need to take some pictures of my paper notebooks and download the sleeping graphs from my phone. Yeesh. So, question for everyone: do you you think having a medical notebook with all your test results and doctor’s notes counts as tracking, or is that completely different?

    • August 3, 2014 at 9:50 am

      Staci you are admirable and your work todwras researching and bringing awareness about Lyme Disease is fantastic. I wish you can push to find a cure and after so much you have done I hope you can be completely recovered and healthy. To all the team, thank you very much.

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  18. nancy
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