Most LLMDs (Lyme Literate Doctors) treat Lyme disease – especially chronic Lyme disease – by pulsing the antibiotics over months or years, which means taking antibiotics for a few weeks or a few months on followed by a few weeks off and so on. This is what I have been doing for the past year. LLMDs may switch medications throughout the treatment based upon the patient’s response and whether or not someone has co-infections that need to be treated, such as Babesia. Some people will see an improvement in their condition on certain antibiotics while others may only see slight or none at all, so it takes a lot of experience and listening to the patient to know which medications to try. Also remember that not all LLMDs are created equal. They often have different protocols and different antibiotics which they prescribe most often.
Not to be discouraging, but it can take a long time to find what antibiotics and/or “alternative” therapies work for you, and what works for some may not work for others. Such is the dilemma with treating Lyme disease. The word “cure” is not attached to any one antibiotic used to treat Lyme. So don’t be too discouraged if you aren’t better in a few months or even a few years as certain antibiotics just won’t work for you while others may.
I take only oral antibiotics – oftentimes, two or three medications concomitantly – as my LLMD feels that you can typically achieve the same results with oral antibiotics without the risks that come with intravenous therapy (e.g., infection, gall bladder complications). However, he does say that some cases do not respond as well or much at all to oral antibiotics and therefore need IV therapy (the drug Rocephin), especially when one has neurological Lyme disease. You should also be aware that many do not respond much to IV therapy either unfortunately, even months or years of it.
The first medication I was put on was Doryx (time-release doxycycline) in order to be able to build up to tetracycline which is more powerful. The Doryx helped a lot at first, but we did not continue with it as he said that at this point, given that I have developed late-stage neurological Lyme, all it would do is put the spirochetes to sleep in a sense, and not do much in the way of killing any off.
Antibiotics I have taken:
Doryx (time-release doxycycline)
Tetracycline + Diflucan
Biaxin + ceftriaxone
Mepron (anti-malarial that can penetrate the cyst form of Lyme; also used for Babesia) + Zithromax
Mepron + Diflucan
Mepron + tetracycline + Diflucan
*Mepron will not be effective alone as it will only penetrate the cyst but will not kill the form of the spirochete inside the cyst.
Note: The Diflucan is not being used to treat a possible yeast overgrowth due to the antibiotics, rather, it is being used because many of those with Lyme disease are getting better taking it for extended periods of time as a result of pioneering work done by Fritz Schardt, a German physician specializing in internal medicine. Dr. Schardt found that when he treated himself and others with chronic Lyme with Diflucan, many of them, including himself, eventually got better, and part of the reason is that he feels Diflucan interferes with the spirochetes’ ability to grow and replicate:
“JN: Tell me your reasoning as to why diflucan might work in chronic lyme.
FS: There are several reasons. First of all, it inhibits an enzyme
called cytochrome P450. This is an enzyme that your liver, for instance, uses to detoxify
chemicals and drugs. Borrelia has a very primitive p450 defense, so if you inhibit it,
it is easily weakened. Therefore I believe that diflucan inhibits the growth and
replication of borrelia. It does not necessarily kill it. In addition, it penetrates
well into the cells and into the nervous system and brain, where borrelia may hide.”
To read the full interview and the abstract of the journal article he published on this, CLICK HERE
I have decided to stop antibiotic therapy after a year and a half as I was not seeing much more progress. What I have decided to do is try experimenting with a Rife-type device (specifically, the GB4000 + Amplifier). It is a frequency generator device that gives off frequencies (low-dose electromagnetic fields) through direct contact. The person’s body is used as a conductor for the frequencies. whereby a person holds metal rods (covered by moistened cotton covers) in their hands, and places their bare feet on metal plates (covered by moistened cotton covers). The electrical current carrying the frequencies is then sent directly through the body, from the hands to the feet, or visa versa, using the body as the conductor. This has been shown to disrupt organisms in the body and thus elicit a “cure” or at least an abatement of symptoms – that is open to debate. I have read much on the use of Rife machines (Note: not all Rife machines are created equal), and have spoken to some fellow-Lyme sufferers who are using the GB4000 and getting well, whereas with antibiotics they had either failed all of them, plateaued or had their symptoms return once off the antibiotics. I was told by a doctor the it is the closest thing he has seen to a cure for Lyme outside of, what is often, long-term antibiotics.
One of the reasons for this may be due to the fact that low dose electromagnetic fields have actually been shown to break up biofilms (whereas antibiotics typically cannot as biofilms are thousands of times more resistant to antibiotics than free-swimming bacteria are) A biofilm is composed of living, reproducing microorganisms, such as the Borrelia bacteria, that exist as a colony, or community. Spirochetes have been shown to form biofilms, and this is one of the theories as to why chronic Lyme develops.
I will keep you posted as to my progress as I have only just begun experimenting with the GB4000 this weekend. In the meantime, here are a few journal articles discussing the use of low-frequency electromagnetic fields to break up biofilms…
Here is a neat video showing Borrelia forming a biofilm